منابع مشابه
A Mycobacterium leprae VNTR database.
A great deal of the last quarter of a century’s astonishing progress in understanding and treating human disease is attributable to the existence of public databases where information about DNA sequences, protein sequences, protein structures, human variation, etc. is stored and is freely available to all interested investigators. Information that is developed by one laboratory to help answer a...
متن کاملVNTR typing of Mycobacterium leprae in South Indian leprosy patients.
OBJECTIVES To study the suitability, stability and diversity of short tandem repeat (STR) genomic markers to elicit strain variation in the Mycobacterium leprae isolates within leprosy patients from Andhra Pradesh and Tamil Nadu states in South India. MATERIALS AND METHODS Slit skin smear (SSS) samples were collected from lesions and various body sites of newly diagnosed leprosy patients. The...
متن کاملDNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)
The study of the transmission of leprosy is particularly difficult since the causative agent, Mycobacterium leprae, cannot be cultured in the laboratory. The only sources of the bacteria are leprosy patients, and experimentally infected armadillos and nude mice. Thus, many of the methods used in modern epidemiology are not available for the study of leprosy. Despite an extensive global drug tre...
متن کاملMycobacterium leprae. A multifactorial approach
Evidence is accumulating that Mycobacterium leprae is probably a microbe dependent microbe. l O1 3 The first report that multiplication of M. leprae was promoted by a growth factor of mycobacterial origin was proposed by Twort l 9 in 1 9 1 0 , two years before the discovery of the cultivation of 'lohne's bacilli' in media enriched with heat-killed mycobacteria . 2o The growth factor was identi...
متن کاملStructure of Mycobacterium leprae.
Introduction : why study structure? Information about the structure of M. leprae may be obtained by microscopy (especially electron miscroscopy) and other physical techniques . There is active development of such techniques , but at present the information they can give about structures as complex as a bac terium is l imited . To obtain a detailed knowledge of the molecular composition and con...
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 2010
ISSN: 2162-8807
DOI: 10.47276/lr.81.2.96